The incarnation: a "new creation"
"The virginal conception “indicates that God himself made a new beginning in the course of the history of his creation by coming himself in person and becoming part of that history. He himself originated this particular human life by a new act of creation. Jesus Christ is not a saviour arising out of the continuity of human history, but God in person intervening in it, coming to the rescue” (Cranfield 1988: 189; cf. Piper 1964: 141-48).
"It is Luke who makes explicit the connection between the virginal conception and Jesus’ divine Sonship: “The child to be born will be holy; he will be called Son of God” (Luke 1:35)." -- Charles H. H. Scobie, "The Ways of Our God", pp. 394, 395